Glucagon-like peptide-1

You should know that Glucagon-like peptide-1
*increases insulin secretion
*increases insulin-sensitivity
*increases beta cells
**decreases food intake by increasing satiety.**
Gastric Bypass => Increases GLP1

Amplify’d from en.wikipedia.org

Glucagon-like peptide-1

Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a gut hormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2. Those peptides results from selective cleavage of the proglucagon molecule.

Physiological functions

GLP-1 possesses several physiological properties that make it (and its analogs) a subject of intensive investigation as a potential treatment of diabetes mellitus.[1][2][3]. The known physiological functions of GLP-1 include:

As a proof of the physiological role of GLP-1 in post-prandial insulin secretion, it has been shown that an oral dose of glucose triggers a much higher peak in plasmatic insulin concentration compared to an intravenous dose.

Read more at en.wikipedia.org

 

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