Benefits of Creatine Supplementation
In sickness and in health: the widespread applic… [Amino Acids. 2011] – PubMed – NCBI http://ow.ly/9qx7f
Amino Acids. 2011 Nov 19. [Epub ahead of print]
In sickness and in health: the widespread application of creatine supplementation.
Gualano B, Roschel H, Lancha-Jr AH, Brightbill CE, Rawson ES.
School of Physical Education and Sport, University of Sao Paulo, Av Mello de Moraes, 65, Butantã, Sao Paulo, SP, 05508-030, Brazil, firstname.lastname@example.org.
There is an extensive and still growing body of the literature supporting the efficacy of creatine (Cr) supplementation. In sports, creatine has been recognized as the most effective nutritional supplement in enhancing exercise tolerance, muscle strength and lean body mass. From a clinical perspective, the application of Cr supplementation is indeed exciting. Evidences of benefits from this supplement have been reported in a broad range of diseases, including myopathies, neurodegenerative disorders, cancer, rheumatic diseases, and type 2 diabetes. In addition, after hundreds of published studies and millions of exposures creatine supplementation maintains an excellent safety profile. Thus, we contend that the widespread application of this supplement may benefit athletes, elderly people and various patient populations. In this narrative review, we aimed to summarize both the ergogenic and therapeutic effects of Cr supplementation.