Thirty women with a body mass index (BMI) > 27 kg/m2 were enrolled to a 4 weeks intervention with a VLCD
Patients lost 35% ± 13% of the excess of weight in only 4 weeks.
Significant improvements in triglycerides, total cholesterol and LDL cholesterol (Low Density Lipoproteins) were observed. Insulin resistance determined by Homeostasis model assessment (HOMA), decreased significantly from 3.3 ± 1.8 to 2.0 ± 0.9 (p = 0.003). No serious adverse events were reported.
Short term use of VLCDs is safe and effective to induce rapid weight loss
Rev Med Chil. 2011 Oct;139(10):1286-91. Epub 2012 Jan 3.
[Efficacy and safety of a very-low-calorie diet in a group of overweight or obese women].
Cuevas A, Cordero MJ, Olivos C, Ghiardo D, Alvarez V.