A strong rationale for citrulline supplementation in short bowel

A strong rationale for citrulline supplementatArginine supplementation seems logical in situations where this amino acid becomes essential, for example after massive intestinal resection. Arginine is taken up and metabolised by the liver to a large extent and its supplementation is potentially unsafe. Citrulline is not captured by the liver and passes freely to the kidneys … Continue reading A strong rationale for citrulline supplementation in short bowel

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Watermelon May Reduce Fat & Improve Diabetes

Watermelon is rich in L-citrulline, an effective precursor of L-arginine. dietary supplementation with watermelon pomace juice or L-arginine increased serum concentrations of arginine; **reduced fat** lowered serum concentrations of **glucose**, free fatty acids, homocysteine, and dimethylarginines; enhanced GTP cyclohydrolase-I activity and tetrahydrobiopterin concentrations in the heart; and improved acetylcholine-induced vascular relaxation.Amplify’d from http://www.ncbi.nlm.nih.govJ Nutr. 2007 … Continue reading Watermelon May Reduce Fat & Improve Diabetes

Citrulline as a supplement for short bowel syndrome patients.

Citrulline as a supplement for short bowel syndrome patients. Only citrulline was able to prevent muscle atrophy and it was achieved independently from any noticeable effect on the gut in particular because citrulline and arginine share the same effect on mucosal ileal protein content. These results suggest that citrulline should be considered as a potential … Continue reading Citrulline as a supplement for short bowel syndrome patients.

Citrulline/Arginine May Help in Wound Healing

Citrulline/Arginine May Help in Wound Healing Human data support previous animal studies suggesting arginine metabolism for an NO- as well as arginase-mediated reparation of injured skin.Amplify’d from http://www.ncbi.nlm.nih.govNitric Oxide. 2009 Nov-Dec;21(3-4):175-83. Epub 2009 Jul 26.Role of arginine in superficial wound healing in man.Debats IB, Wolfs TG, Gotoh T, Cleutjens JP, Peutz-Kootstra CJ, van der Hulst … Continue reading Citrulline/Arginine May Help in Wound Healing

Warning! Citrulline May Decrease After Gastric Bypass

Warning! Citrulline May Decrease After Gastric Bypass In experimental intestinal resection, arginine availability decreases as intestinal citrulline synthesis decreases. Supplemental Oral Citrulline and Creatine may be of value!Amplify’d from http://www.ncbi.nlm.nih.govCurr Opin Clin Nutr Metab Care. 2010 Jan;13(1):65-9.Effect of intestinal resections on arginine metabolism: practical implications for nutrition support.Crenn P, Cynober L.SourceLaboratoire de Biologie de Nutrition, … Continue reading Warning! Citrulline May Decrease After Gastric Bypass

Citrulline / Arginine May Help in “Short Bowel” Syndrome

Citrulline / Arginine May Help in "Short Bowel" Syndrome "Chronic dietary arginine supplementation in PEN pigs induced mucosal growth in the intestine"Amplify’d from http://www.ncbi.nlm.nih.govJ Nutr. 2011 Jan;141(1):63-70. Epub 2010 Nov 24.Enteral arginine does not increase superior mesenteric arterial blood flow but induces mucosal growth in neonatal pigs.Puiman PJ, Stoll B, van Goudoever JB, Burrin DG.SourceDepartment … Continue reading Citrulline / Arginine May Help in “Short Bowel” Syndrome